Linked Life Data

1388326

Source:http://linkedlifedata.com/resource/pubmed/id/1388326

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1992-10-22
pubmed:abstractText
Although Doppler catheter recordings are used to determine coronary flow velocity, their accuracy in the estimation of volumetric blood flow has not been validated. To address this issue, Doppler-derived coronary flow was measured in a canine model and compared with that obtained by means of an electromagnetic flowmeter. A carotid artery-to-circumflex coronary artery shunt was created in six dogs with tubing that incorporated an inline electromagnetic flow device. The circumflex artery was occlusively cannulated by means of a rigid metal stent of known internal diameter, which was placed 2 cm into the vessel, and flow was measured in the stent region by means of a 3F Doppler catheter. Analysis of Doppler shift signals was performed by means of a zero-crossing detector (ZCD) and an off-line fast-Fourier transformation (FFT) system. Flow derived from peak FFT velocities corresponded closely to electromagnetic flow (slope 1.09, r = 0.93), whereas mean FFT and ZCD velocities underestimated electromagnetic flow (with slopes of 0.47 and 0.46, respectively) despite a close correlation (r = 0.92, 0.94). Thus FFT analysis of the Doppler signal with determination of peak velocity gives the most accurate representation of flow, whereas measurements based on ZCD mean velocities may significantly underestimate coronary flow.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0002-8703
pubmed:author
pubmed:issnType
Print
pubmed:volume
124
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
870-5
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Measurement of volumetric coronary blood flow with a Doppler catheter: validation in an animal model.
pubmed:affiliation
Cardiovascular Research Institute, University of California, San Francisco 94143.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't