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A simple method has been described by which the action of drugs on the stress-induced block in milk ejection can be investigated on lactating guinea-pigs. Reserpine, meprobamate and chlorpromazine when administered to the lactating mother at various periods before suckling reduced the block in milk ejection caused by the stress. Dibenamine and dichloroisoprenaline did not affect in any way the stress-induced block. It is suggested that the stress-induced block in milk ejection is probably a nervous block and not mediated through adrenaline.
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