Linked Life Data

1385583

Source:http://linkedlifedata.com/resource/pubmed/id/1385583

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1992-8-11
pubmed:abstractText
Under certain conditions, dark-reared chicks preferentially approach objects resembling conspecifics. In the current study we investigated the effect of the catecholaminergic neurotoxin DSP4 on this predisposition. After hatching, chicks received an intraperitoneal injection of either DSP4 or vehicle (controls). The chicks were individually placed in running wheels for 2 x 1 hr, 24 hr before testing. The chicks were maintained in darkness until given a preference test, which involved the simultaneous presentation of an illuminated red box and a stuffed fowl at 36, 48, 60, 66, or 72 hr after hatching. The approach of each chick toward the two objects was recorded over 5 min and a preference score calculated. Control chicks placed in the running wheels at 24 and 36 hr posthatch and tested 24 hr later showed a significant preference for the fowl compared to the red box. In contrast, DSP4-treated chicks did not show such a preference at corresponding ages, but did express a greater preference for the fowl when placed in the running wheels at 42 and 48 hr posthatch and tested 24 hr later. These results suggest that experience of the running wheel or of associated factors, e.g., handling, must occur during a restricted period of time to influence the emergence of the predisposition to approach the stuffed fowl. DSP4 treatment delays the onset of this period.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0012-1630
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
251-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
The effect of the neurotoxin DSP4 on the development of a predisposition in the domestic chick.
pubmed:affiliation
Department of Anatomy, St. George's Hospital Medical School, London, U.K.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't