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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1977-3-21
|
| pubmed:abstractText |
The avidity of antibodies to DNA in the sera of 8 patients with SLE was determined by saturation analysis and Scatchard plots. Five of the patients had severe lupus nephritis; the other 3 had relatively mild or no kidney disease. The Scatchard plots revealed components with high relative avidity in the patients with severe nephritis (K values 4.4-10.4 X 10(5) M-1 for nDNA), compared with the patients who had mild or no kidney disease (K values 0.3-1.8 X 10(5) M-1 for nDNA). Avidity measurements may be helpful in the evaluation and treatment of patients with SLE.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0004-3591
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
20
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
23-9
|
| pubmed:dateRevised |
2011-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:138425-Affinity Labels,
pubmed-meshheading:138425-Autoantibodies,
pubmed-meshheading:138425-Binding Sites, Antibody,
pubmed-meshheading:138425-DNA,
pubmed-meshheading:138425-Glomerulonephritis,
pubmed-meshheading:138425-Humans,
pubmed-meshheading:138425-Immune Complex Diseases,
pubmed-meshheading:138425-Kidney,
pubmed-meshheading:138425-Lupus Erythematosus, Systemic,
pubmed-meshheading:138425-Prognosis
|
| pubmed:articleTitle |
Avidity of antibodies in SLE: relation to severity of renal involvement.
|
| pubmed:publicationType |
Journal Article
|