Linked Life Data

1383953

Source:http://linkedlifedata.com/resource/pubmed/id/1383953

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10 Pt 1
pubmed:dateCreated
1992-11-25
pubmed:abstractText
During the last decade dynamic cardiomyoplasty has been introduced as a new method to treat patients with severe heart failure. This procedure consists of the wrapping of the latissimus dorsi (LD) muscle around the heart with electrical stimulation of the muscle synchronous to cardiac contraction. The optimal pacing mode of the muscle, during the conditioning and working period of the LD muscle, is still unclear. The pace protocol, currently used worldwide, has a maximal number of muscle tetanic contractions of 100 per minute. Data are presented on the LD muscle contraction characteristics using that protocol. Both force measurements from six in situ stimulated goat LD muscles and x-ray evaluation of the movement of metallic clips on wrapped LD muscles in two patients were used. Results demonstrate that LD muscle force is well maintained at the maximal rate of 100 contractions per minute but relaxation is severely hampered. This may lead to diminished support of the failing heart and damage of the wrapped muscle. A pacing protocol is proposed using a lower maximal stimulation rate.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0147-8389
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1430-6
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
The importance of muscle relaxation in dynamic cardiomyoplasty.
pubmed:affiliation
Department of Cardiology, Academic Hospital Maastricht, The Netherlands.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't