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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1992-11-10
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pubmed:abstractText |
Twenty-seven patients with metastatic nonseminomatous germ cell tumors were treated with Cisplatin, vinblastine, bleomycin, and low-dose methotrexate (PVB+M) combinations. Patients were divided into good-risk and poor-risk groups. All seven patients (100%) with good-risk factors achieved complete response, and all are alive disease free at a median of 70 months. In the poor-risk group, only 10 of 20 patients (50%) achieved complete response, and seven (35%) are alive disease free at a median of 58 months. Eight patients, 4 in each group, were required to undergo surgery for removal of postchemotherapy residual masses. The results confirm that Cisplatin-based chemotherapy protocols are adequate to cure most patients with good-risk factors, and newer approaches are needed for patients at poor risk.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0022-4790
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
51
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
100-3
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pubmed:dateRevised |
2006-4-24
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pubmed:meshHeading |
pubmed-meshheading:1383638-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:1383638-Bleomycin,
pubmed-meshheading:1383638-Cisplatin,
pubmed-meshheading:1383638-Follow-Up Studies,
pubmed-meshheading:1383638-Humans,
pubmed-meshheading:1383638-Male,
pubmed-meshheading:1383638-Methotrexate,
pubmed-meshheading:1383638-Neoplasms, Germ Cell and Embryonal,
pubmed-meshheading:1383638-Risk Factors,
pubmed-meshheading:1383638-Survival Rate,
pubmed-meshheading:1383638-Testicular Neoplasms,
pubmed-meshheading:1383638-Time Factors,
pubmed-meshheading:1383638-Vinblastine
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pubmed:year |
1992
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pubmed:articleTitle |
Cisplatin-based (PVB+M) chemotherapy in good-risk and poor-risk nonseminomatous germ cell tumors.
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pubmed:affiliation |
Department of Medical Oncology, Tata Memorial Hospital, Bombay, India.
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pubmed:publicationType |
Journal Article
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