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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2-3
|
| pubmed:dateCreated |
1992-11-13
|
| pubmed:abstractText |
On exposure to triphosphatic nucleotides vas deferens DDT1 MF-2 smooth muscle cells responded with an outward K+ current as measured with the whole-cell patch clamp configuration. The rank order of potency was: ATP greater than UTP greater than TTP greater than CTP = GTP. The responses evoked by these agonists were blocked by suramin. Adenosine, ADP, alpha, beta-methylene-ATP and 2-methylthio-ATP did not affect the transmembrane current. The responses evoked by the nucleotides in DDT1 MF-2 cells are supposed to be mediated via 'nucleotide' receptors.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0014-2999
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
14
|
| pubmed:volume |
215
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
317-20
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:1383000-Adenosine Triphosphate,
pubmed-meshheading:1383000-Animals,
pubmed-meshheading:1383000-Cells, Cultured,
pubmed-meshheading:1383000-Ion Channels,
pubmed-meshheading:1383000-Male,
pubmed-meshheading:1383000-Muscle, Smooth,
pubmed-meshheading:1383000-Nucleotides,
pubmed-meshheading:1383000-Receptors, Cell Surface,
pubmed-meshheading:1383000-Vas Deferens
|
| pubmed:year |
1992
|
| pubmed:articleTitle |
Nucleotide receptors on DDT1 MF-2 vas deferens cells.
|
| pubmed:affiliation |
Department of Pharmacology/Clinical Pharmacology, University of Groningen, Netherlands.
|
| pubmed:publicationType |
Journal Article
|