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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
|
pubmed:dateCreated |
1992-10-15
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pubmed:abstractText |
Electrochemotherapy (ECT) is a new antitumour treatment which consists of delivering electric pulses to the tumour a few minutes after an intravenous injection of bleomycin. The antitumour efficacy of ECT is increased by local injections of interleukin 2 (IL2) in the oedema which appears at the site of the treated tumours. We have shown that tumour cells inoculated in syngeneic mice are rejected if IL2 secreting allo- or xenogeneic cells are co-injected with tumour cells. We report here the large increase of ECT therapeutical efficacy when allogeneic cells secreting IL2 are injected into the peri-tumoural oedema.
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pubmed:language |
fre
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0764-4469
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
314
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
539-44
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1381659-Animals,
pubmed-meshheading:1381659-Bleomycin,
pubmed-meshheading:1381659-Edema,
pubmed-meshheading:1381659-Electrochemistry,
pubmed-meshheading:1381659-Female,
pubmed-meshheading:1381659-Immunotherapy,
pubmed-meshheading:1381659-Injections, Intravenous,
pubmed-meshheading:1381659-Interleukin-2,
pubmed-meshheading:1381659-Mice,
pubmed-meshheading:1381659-Mice, Inbred C57BL,
pubmed-meshheading:1381659-Neoplasm Transplantation,
pubmed-meshheading:1381659-Neoplasms,
pubmed-meshheading:1381659-Sarcoma, Experimental,
pubmed-meshheading:1381659-Skin Diseases,
pubmed-meshheading:1381659-Transplantation, Homologous
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pubmed:year |
1992
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pubmed:articleTitle |
[Potentiation of the antitumoral effect of electrochemotherapy by immunotherapy with allogeneic cells producing interleukin 2].
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pubmed:affiliation |
Unité de Biochimie-Enzymologie de l'I.G.R., U.R.A. 147 C.N.R.S., U. 140, I.N.S.E.R.M., Institut Gustave-Roussy, Villejuif.
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
|