Linked Life Data

1380944

Source:http://linkedlifedata.com/resource/pubmed/id/1380944

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1992-9-28
pubmed:abstractText
Haplotypes or subhaplotypes in the beta-globin gene cluster were examined in 31 normal Japanese and 21 Korean families. Major haplotypes were VII, V, and I, which shared a common subhaplotype [+----], and occurred in 70% of the Japanese and 68% of the Koreans. Three haploypes which shared a common subhaplotype [-+-++], bearing the XmnI site 5' to the G gamma-globin gene, occurred in 13% of the Japanese and 7.3% of the Koreans. One subhaplotype [-++-+], which is closely linked to the A gamma T-globin gene, had an incidence of 6.6% in the Japanese and 20% in the Koreans. Rare subhaplotypes [---++], and [- +] which has been observed mainly in Melanesians and Polynesians, and a very rare subhaplotype [-----] were observed. The present study suggests that high or low G gamma-globin chain production is closely related to subhaplotypes [-+-++] and [+----], respectively, among the normal adult population.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-5652
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
216-21
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Relationships between %Hb F or %G gamma and the haplotypes in the beta-globin gene cluster in the normal adult Japanese and Korean populations.
pubmed:affiliation
Department of Morphology, Institute for Developmental Research Aichi Prefectural Colony, Japan.
pubmed:publicationType
Journal Article