Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1992-9-22
pubmed:abstractText
Glutamate is the principal excitatory neurotransmitter in the brain. Glutamate activates cation-selective receptor channels carried by nearly every neuron and by glial cells. Bernd Sommer and Peter Seeburg describe how our concepts concerning the molecular and functional design of ionotropic glutamate receptors are rapidly progressing, with the recent discovery of novel receptor properties and new subunits following the landmark cloning of the first receptor subunit by M. Hollmann and his colleagues. New properties currently revealed by the cloned receptor channels may guide physiologists in characterizing the elementary steps in synaptic transmission, help neurologists to define the role of glutamate receptors in acute and chronic neuropathologies, and enlighten all neuroscientists whose models for learning and memory involve the idiosyncracies of particular channel subtypes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0165-6147
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
291-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Glutamate receptor channels: novel properties and new clones.
pubmed:affiliation
Laboratory of Neuroendocrinology, ZMBH, University of Heidelberg, Germany.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't