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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1992-9-24
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pubmed:abstractText |
We retrospectively reviewed 29 cases of ventral abdominal wall defects to evaluate the usefulness of amniotic fluid markers in the prenatal assessment of those disorders. Amniotic fluid alpha-fetoprotein (AF-AFP) values were available in 17 cases diagnosed prior to 22 weeks' gestation and acetylcholinesterase (AF-ACE) values, in 21 cases. All 7 fetuses with a gastroschisis had an elevated AF-AFP, while only 2 of the 10 fetuses with an omphalocele had elevated values (P = .002). ACE was present in 80% of the cases of gastroschisis versus 27.3% of the cases of omphalocele (P = .03). With equivocal sonographic findings, a normal AF-AFP and negative AF-ACE may be more compatible with an omphalocele.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0024-7758
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
445-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1380559-Acetylcholinesterase,
pubmed-meshheading:1380559-Alabama,
pubmed-meshheading:1380559-Amniotic Fluid,
pubmed-meshheading:1380559-Biological Markers,
pubmed-meshheading:1380559-Diagnosis, Differential,
pubmed-meshheading:1380559-Female,
pubmed-meshheading:1380559-Hernia, Umbilical,
pubmed-meshheading:1380559-Hernia, Ventral,
pubmed-meshheading:1380559-Hospitals, University,
pubmed-meshheading:1380559-Humans,
pubmed-meshheading:1380559-Infant, Newborn,
pubmed-meshheading:1380559-Pregnancy,
pubmed-meshheading:1380559-Pregnancy Outcome,
pubmed-meshheading:1380559-Prenatal Diagnosis,
pubmed-meshheading:1380559-Retrospective Studies,
pubmed-meshheading:1380559-Sensitivity and Specificity,
pubmed-meshheading:1380559-Ultrasonography, Prenatal,
pubmed-meshheading:1380559-alpha-Fetoproteins
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pubmed:year |
1992
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pubmed:articleTitle |
Prenatal differentiation of ventral abdominal wall defects. Are amniotic fluid markers useful adjuncts?
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pubmed:affiliation |
Department of Obstetrics and Gynecology, University of Alabama, Birmingham 35233-7333.
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pubmed:publicationType |
Journal Article
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