rdf:type |
|
lifeskim:mentions |
umls-concept:C0008657,
umls-concept:C0017340,
umls-concept:C0205108,
umls-concept:C0453946,
umls-concept:C0458003,
umls-concept:C0591833,
umls-concept:C0596988,
umls-concept:C0678723,
umls-concept:C0796345,
umls-concept:C1522408,
umls-concept:C1705944
|
pubmed:issue |
1
|
pubmed:dateCreated |
1992-9-10
|
pubmed:abstractText |
We have identified restriction fragment length polymorphisms between Mus musculus and Mus spretus for the Chromosome 15 loci Hox-3, Wnt-1, Krt-2, Rar-g, and Ly-6. We followed the inheritance of these alleles in interspecific genetic test crosses between velvet coat (Ve) heterozygotes and M. spretus. The results suggest a gene order and recombination distances (in cM) of Ly-6-22-Wnt-1-2-Ve/Krt-2/Rar-g-3-Hox-3. No recombination was found between Ve, Krt-2, and Rar-g. The data also provide evidence for the hypothesis of a large-scale genomic duplication involving homologous gene pairs on mouse Chromosomes 15 and 11.
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pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Homeodomain Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Hoxc8 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Keratins,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Retinoic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Wnt Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Wnt1 Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Wnt1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Zebrafish Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
|
pubmed:issn |
0022-104X
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
263
|
pubmed:geneSymbol |
Hox-3.1,
Krt-2,
Rar-g,
Wnt-1
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
83-95
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:1379621-Animals,
pubmed-meshheading:1379621-Carrier Proteins,
pubmed-meshheading:1379621-Chromosome Mapping,
pubmed-meshheading:1379621-Crosses, Genetic,
pubmed-meshheading:1379621-DNA-Binding Proteins,
pubmed-meshheading:1379621-Female,
pubmed-meshheading:1379621-Genes,
pubmed-meshheading:1379621-Genes, Developmental,
pubmed-meshheading:1379621-Genes, Homeobox,
pubmed-meshheading:1379621-Genetic Linkage,
pubmed-meshheading:1379621-Hair,
pubmed-meshheading:1379621-Homeodomain Proteins,
pubmed-meshheading:1379621-Keratins,
pubmed-meshheading:1379621-Male,
pubmed-meshheading:1379621-Mice,
pubmed-meshheading:1379621-Mice, Inbred BALB C,
pubmed-meshheading:1379621-Mutation,
pubmed-meshheading:1379621-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:1379621-Proto-Oncogene Proteins,
pubmed-meshheading:1379621-Receptors, Retinoic Acid,
pubmed-meshheading:1379621-Wnt Proteins,
pubmed-meshheading:1379621-Wnt1 Protein,
pubmed-meshheading:1379621-Zebrafish Proteins
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pubmed:year |
1992
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pubmed:articleTitle |
Genetic linkage analysis of the murine developmental mutant velvet coat (Ve) and the distal chromosome 15 developmental genes Hox-3.1, Rar-g, Wnt-1, and Krt-2.
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pubmed:affiliation |
Department of Biology, Yale University, New Haven, Connecticut 06511.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|