Linked Life Data

1375444

Source:http://linkedlifedata.com/resource/pubmed/id/1375444

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1992-6-23
pubmed:abstractText
The early development of myelination was studied by means of myelin basic protein (MBP) and luxol fast blue (LFB) stainings of large sections of the cerebral hemispheres. Myelination first occurs in the globus pallidus, pallidothalamic fibers of the posterior internal capsule and the thalamus at 25 weeks, which may be related to the cellular maturation in the globus pallidus and thalamus. Then myelination is observed in the striatum, and precentral and postcentral gyri at 35 weeks, and the anterior internal capsule and optic radiation at 37 weeks. Immunoreactivity with MBP is observed earlier and more strongly in the early myelination period than that with LFB. Thus, MBP may play an important role in myelination and its delay. The macroscopic positivity as to MBP as well as LFB staining may be related to the development of high signal intensity observed in a T1-weighted magnetic resonance imaging, which was observed 1 to 3 months after the first microscopic appearance of myelin.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0387-7604
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-6
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Development of myelination in the human fetal and infant cerebrum: a myelin basic protein immunohistochemical study.
pubmed:affiliation
Division of Mental Retardation and Birth Defect Research, National Institute of Neuroscience, NCNP, Tokyo, Japan.
pubmed:publicationType
Journal Article