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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1992-6-15
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pubmed:abstractText |
In order to investigate the usefulness of polysaccharides as carriers for the induction of antibody to synthetic peptides, peptides representing residues 139-147 of the surface antigen of hepatitis B and residues 129-140 of the pre-S2 region of the protein were coupled to mannan and dextran via an aminocaproic spacer molecule. Of the two conjugates studied, only mannan was useful as a carrier for the efficient production of anti-peptide antibodies.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0022-1759
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
149
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
127-31
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:1374776-Aminocaproic Acids,
pubmed-meshheading:1374776-Animals,
pubmed-meshheading:1374776-Antibodies, Anti-Idiotypic,
pubmed-meshheading:1374776-Antibody Specificity,
pubmed-meshheading:1374776-Dextrans,
pubmed-meshheading:1374776-Dose-Response Relationship, Immunologic,
pubmed-meshheading:1374776-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:1374776-Hepatitis B Surface Antigens,
pubmed-meshheading:1374776-Immunotoxins,
pubmed-meshheading:1374776-Male,
pubmed-meshheading:1374776-Mannans,
pubmed-meshheading:1374776-Mice,
pubmed-meshheading:1374776-Mice, Inbred BALB C
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pubmed:year |
1992
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pubmed:articleTitle |
Production of anti-peptide specific antibody in mice following immunization with peptides conjugated to mannan.
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pubmed:affiliation |
Department of Clinical Sciences, London School of Hygiene and Tropical Medicine, UK.
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pubmed:publicationType |
Journal Article
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