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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1992-6-12
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pubmed:abstractText |
To assess the effects of verapamil on postextrasystolic potentiation (PESP), contrast left ventriculography was performed in ten healthy anesthetized dogs before and after the intravenous administration of verapamil, 0.1 mg/kg. During the contrast ventriculography, a single atrial premature stimulus was introduced. Ejection fractions of a control beat and postpremature beat were measured before and after verapamil. Before verapamil, the mean ejection fractions of the control beat and the postpremature beat were 60 +/- 10 percent and 67 +/- 10 percent, respectively (p less than 0.05). Following the administration of verapamil, the mean ejection fraction of the control beat decreased from 60 +/- 10 percent to 55 +/- 11 percent (p less than 0.05). However, the mean ejection fraction of the postpremature beats increased when compared with the control beats following intravenous verapamil (65 +/- 8 percent and 55 +/- 11 percent, respectively; p less than 0.05). These results suggest that PESP is not inhibited by the administration of intravenous verapamil.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0012-3692
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
101
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1438-41
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:1374699-Animals,
pubmed-meshheading:1374699-Blood Pressure,
pubmed-meshheading:1374699-Cardiac Complexes, Premature,
pubmed-meshheading:1374699-Dogs,
pubmed-meshheading:1374699-Heart Rate,
pubmed-meshheading:1374699-Myocardial Contraction,
pubmed-meshheading:1374699-Stroke Volume,
pubmed-meshheading:1374699-Verapamil
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pubmed:year |
1992
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pubmed:articleTitle |
Effects of verapamil on postextrasystolic potentiation.
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pubmed:affiliation |
Division of Cardiology, Creighton University School of Medicine, Omaha.
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pubmed:publicationType |
Journal Article
|