pubmed-article:1369452 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:1369452 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
pubmed-article:1369452 | lifeskim:mentions | umls-concept:C0036536 | lld:lifeskim |
pubmed-article:1369452 | lifeskim:mentions | umls-concept:C0036537 | lld:lifeskim |
pubmed-article:1369452 | lifeskim:mentions | umls-concept:C0441889 | lld:lifeskim |
pubmed-article:1369452 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
pubmed-article:1369452 | lifeskim:mentions | umls-concept:C1422036 | lld:lifeskim |
pubmed-article:1369452 | lifeskim:mentions | umls-concept:C0013138 | lld:lifeskim |
pubmed-article:1369452 | lifeskim:mentions | umls-concept:C1291802 | lld:lifeskim |
pubmed-article:1369452 | lifeskim:mentions | umls-concept:C0033268 | lld:lifeskim |
pubmed-article:1369452 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
pubmed-article:1369452 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
pubmed-article:1369452 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
pubmed-article:1369452 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:1369452 | pubmed:dateCreated | 1991-7-17 | lld:pubmed |
pubmed-article:1369452 | pubmed:abstractText | We have established a stable, continuous culture Drosophila Schneider 2 cell line that efficiently expresses a secreted, truncated form of the HIV envelope gp120 protein in a regulated manner. The Drosophila produced recombinant gp120 protein is highly glycosylated, is recognized by gp120-specific monoclonal antibodies, binds to the CD4 receptor and has the ability to inhibit syncytia formation between uninfected CD4+ cells and HIV infected cells. We conclude that this recombinant Drosophila envelope protein is an appropriate mimic of the authentic viral envelope protein. Thus, the Drosophila cell provides a continuous, stable culture system for the efficient expression of secreted forms of complex surface glycoproteins in quantities sufficient for detailed analyses. | lld:pubmed |
pubmed-article:1369452 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1369452 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1369452 | pubmed:language | eng | lld:pubmed |
pubmed-article:1369452 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1369452 | pubmed:citationSubset | B | lld:pubmed |
pubmed-article:1369452 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1369452 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:1369452 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1369452 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:1369452 | pubmed:month | Feb | lld:pubmed |
pubmed-article:1369452 | pubmed:issn | 0733-222X | lld:pubmed |
pubmed-article:1369452 | pubmed:author | pubmed-author:RosenbergMM | lld:pubmed |
pubmed-article:1369452 | pubmed:author | pubmed-author:BeckJJ | lld:pubmed |
pubmed-article:1369452 | pubmed:author | pubmed-author:MatthewsT JTJ | lld:pubmed |
pubmed-article:1369452 | pubmed:author | pubmed-author:JohansenHH | lld:pubmed |
pubmed-article:1369452 | pubmed:author | pubmed-author:ColeD JDJ | lld:pubmed |
pubmed-article:1369452 | pubmed:author | pubmed-author:DelersAA | lld:pubmed |
pubmed-article:1369452 | pubmed:author | pubmed-author:HellmigBB | lld:pubmed |
pubmed-article:1369452 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:1369452 | pubmed:volume | 9 | lld:pubmed |
pubmed-article:1369452 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:1369452 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:1369452 | pubmed:pagination | 173-7 | lld:pubmed |
pubmed-article:1369452 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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pubmed-article:1369452 | pubmed:year | 1991 | lld:pubmed |
pubmed-article:1369452 | pubmed:articleTitle | Regulated expression allows high level production and secretion of HIV-1 gp120 envelope glycoprotein in Drosophila Schneider cells. | lld:pubmed |
pubmed-article:1369452 | pubmed:affiliation | Department of Protein Biochemistry, SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania 19406. | lld:pubmed |
pubmed-article:1369452 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:1369452 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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