13680158

Source:http://linkedlifedata.com/resource/pubmed/id/13680158

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0008059, umls-concept:C0021270, umls-concept:C0031327, umls-concept:C0032659, umls-concept:C0076080, umls-concept:C0085136, umls-concept:C0205225, umls-concept:C0870883
pubmed:issue	6
pubmed:dateCreated	2003-11-17
pubmed:abstractText	To construct a population pharmacokinetic model for temozolomide (TMZ), a novel imidazo-tetrazine methylating agent and its metabolites MTIC and AIC in infants and children with primary central nervous system tumors.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/CA 23099, http://linkedlifedata.com/resource/pubmed/grant/CA21765
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7806519
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/5-(3-methyl-1-triazeno)imidazole-4-c..., http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, Alkylating, http://linkedlifedata.com/resource/pubmed/chemical/Dacarbazine, http://linkedlifedata.com/resource/pubmed/chemical/temozolomide
pubmed:status	MEDLINE
pubmed:month	Dec
pubmed:issn	0344-5704
pubmed:author	pubmed-author:FouladiMaryamM, pubmed-author:GajjarAmarA, pubmed-author:HeidemanRichard LRL, pubmed-author:KirsteinMark NMN, pubmed-author:NairGeetaG, pubmed-author:PanettaJohn CJC, pubmed-author:StewartClinton FCF, pubmed-author:WilkinsonMarkM
pubmed:issnType	Print
pubmed:volume	52
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	435-41
pubmed:dateRevised	2007-11-14
pubmed:meshHeading	pubmed-meshheading:13680158-Adolescent, pubmed-meshheading:13680158-Adult, pubmed-meshheading:13680158-Age Factors, pubmed-meshheading:13680158-Antineoplastic Agents, Alkylating, pubmed-meshheading:13680158-Area Under Curve, pubmed-meshheading:13680158-Biological Availability, pubmed-meshheading:13680158-Body Surface Area, pubmed-meshheading:13680158-Brain Neoplasms, pubmed-meshheading:13680158-Child, pubmed-meshheading:13680158-Child, Preschool, pubmed-meshheading:13680158-Chromatography, High Pressure Liquid, pubmed-meshheading:13680158-Dacarbazine, pubmed-meshheading:13680158-Female, pubmed-meshheading:13680158-Humans, pubmed-meshheading:13680158-Infant, pubmed-meshheading:13680158-Linear Models, pubmed-meshheading:13680158-Male, pubmed-meshheading:13680158-Metabolic Clearance Rate, pubmed-meshheading:13680158-Reproducibility of Results
pubmed:year	2003
pubmed:articleTitle	Population pharmacokinetics of temozolomide and metabolites in infants and children with primary central nervous system tumors.
pubmed:affiliation	Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38105, USA.
pubmed:publicationType	Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't, Clinical Trial, Phase II