Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2003-9-18
pubmed:abstractText
In minimal change nephrotic syndrome (MNCS), the most common primary nephrotic syndrome in children, approximately 95% of cases show excellent responses to steroid therapy. However, responding patients may become steroid dependent and experience serious side effects. Although oral cyclophosphamide has been recommended in these patients, long-term side effects such as gonadal toxicity are an important concern. Therefore, cyclophosphamide pulses given intravenously may provide an option that maintains remission with less-frequent side effects.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0931-0509
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2054-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:13679480-Child, pubmed-meshheading:13679480-Child, Preschool, pubmed-meshheading:13679480-Cyclophosphamide, pubmed-meshheading:13679480-Dose-Response Relationship, Drug, pubmed-meshheading:13679480-Drug Administration Schedule, pubmed-meshheading:13679480-Drug Therapy, Combination, pubmed-meshheading:13679480-Female, pubmed-meshheading:13679480-Follow-Up Studies, pubmed-meshheading:13679480-Humans, pubmed-meshheading:13679480-Infusions, Intravenous, pubmed-meshheading:13679480-Male, pubmed-meshheading:13679480-Maximum Tolerated Dose, pubmed-meshheading:13679480-Nephrosis, Lipoid, pubmed-meshheading:13679480-Prednisolone, pubmed-meshheading:13679480-Probability, pubmed-meshheading:13679480-Prospective Studies, pubmed-meshheading:13679480-Pulse Therapy, Drug, pubmed-meshheading:13679480-Recurrence, pubmed-meshheading:13679480-Treatment Failure
pubmed:year
2003
pubmed:articleTitle
Pulse cyclophosphamide inadequately suppresses reoccurrence of minimal change nephrotic syndrome in corticoid-dependent children.
pubmed:affiliation
Urology and Nephrology Center, Mansoura University, Mansoura, Egypt. afdonia@hotmail.com
pubmed:publicationType
Journal Article, Comparative Study