Linked Life Data

1365764

Source:http://linkedlifedata.com/resource/pubmed/id/1365764

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-4
pubmed:dateCreated
1995-3-7
pubmed:abstractText
Ultrastructure of liver biopsy specimens obtained from normal and hepatitis B (HBV) and hepatitis C virus (HCV) infected livers of patients and chimpanzees were compared. Nuclear alterations (glycogen particles, nuclear bodies, "vermicellar bodies", etc.), intracytoplasmic crystalloid inclusions were observed before and after the HBV and HCV infections both in human and chimpanzee hepatocytes, however, some of them were more common during the viral infection. Extreme endoplasmic reticulum dilatation characterized the human, while the presence of membranous cytoplasmic inclusions the hepatocytes of chimpanzees during HCV infection. Interferon-associated membrane alterations were noted during acute or chronic hepatitis, however, in slightly different forms in humans and chimpanzees. Data suggest to be precautions in the interpretation of the ultrastructural alteration observed in different species even to be so closely related as humans and chimpanzees especially during infection with hepatotropic viruses.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0236-5391
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
203-14
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Ultrastructure of normal and hepatitis virus infected human and chimpanzee liver: similarities and differences.
pubmed:affiliation
First Dept. of Pathology and Experimental Cancer Research, Semmelweis Medical University, Budapest, Hungary.
pubmed:publicationType
Journal Article, Comparative Study