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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1993-3-3
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pubmed:abstractText |
Synaptic vesicles have important roles in the neural transmission at nerve terminals: the storage and the controlled exocytosis of neurotransmitters. At least two different factors are responsible for the concentration process: the vacuolar-type H(+)-ATPase (V-ATPase), establishing an electrochemical gradient of protons, and specific transport systems for transmitters. We will discuss our recent progress on the energy-transducing systems in synaptic vesicles: (1) structural aspects of V-ATPase; (2) energy coupling of transport of transmitters; (3) reconstitution of transporters; (4) effects of neurotoxins and neuron blocking agents; (5) function of synaptic-vesicle-like microvesicles from endocrine tissues.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0022-0949
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
172
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
171-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1362770-Adenosine Triphosphatases,
pubmed-meshheading:1362770-Animals,
pubmed-meshheading:1362770-Molecular Structure,
pubmed-meshheading:1362770-Neurosecretory Systems,
pubmed-meshheading:1362770-Neurotransmitter Agents,
pubmed-meshheading:1362770-Synaptic Vesicles,
pubmed-meshheading:1362770-Vacuolar Proton-Translocating ATPases,
pubmed-meshheading:1362770-Vacuoles
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pubmed:year |
1992
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pubmed:articleTitle |
The role of V-ATPase in neuronal and endocrine systems.
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pubmed:affiliation |
Department of Organic Chemistry and Biochemistry, Osaka University, Japan.
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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