Linked Life Data

13587548

Source:http://linkedlifedata.com/resource/pubmed/id/13587548

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1959-12-1
pubmed:abstractText
Axoplasmic changes were studied in the saphenous nerve of the albino rat during the early stages of Wallerian degeneration. The axons were examined at 0, 24, and 48 hours after the surgical transection of the nerve. The material was fixed in 2 per cent OsO(4) in phosphate buffer (pH 7.2-7.5) with sucrose (added to a final osmolar concentration of approximately 0.37 M). The earliest changes were seen in the endoplasmic reticulum which became fragmented into rows of small vesicles. Then, between 24 and 48 hours, the neurofilaments underwent complete disintegration and the axoplasm became filled with finely granular material which later formed irregular clumps surrounded by a structureless matrix, probably fluid in vivo. The fragmentation of the neurofilaments was accompanied by pronounced swelling of the mitochondria.
pubmed:commentsCorrections
pubmed:keyword
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
OM
pubmed:status
OLDMEDLINE
pubmed:month
Sep
pubmed:issn
0095-9901
pubmed:author
pubmed:issnType
Print
pubmed:day
25
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
551-5
pubmed:dateRevised
2010-6-22
pubmed:meshHeading
pubmed:year
1958
pubmed:articleTitle
The early changes in the axoplasm during wallerian degeneration.
pubmed:publicationType
Journal Article