Linked Life Data

1357880

Source:http://linkedlifedata.com/resource/pubmed/id/1357880

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1992-11-23
pubmed:abstractText
Cinnamic alcohol and cinnamic aldehyde are a cause of allergic contact dermatitis in man and give rise to similar rates of positive reactions in routine patch testing. However, data from animal models indicates that the aldehyde is the stronger sensitizer of the two. Circumstantial evidence has pointed to the conversion of alcohol to aldehyde in skin as the cause of cinnamic alcohol sensitization. This report discusses the subject in the light of studies of skin metabolism of cinnamic alcohol. Evidence of limited cross reactivity between cinnamic alcohol and cinnamic aldehyde is supported by data showing conversion of cinnamic alcohol to cinnamic aldehyde by an epidermal enzyme.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0001-5555
pubmed:author
pubmed:issnType
Print
pubmed:volume
72
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
264-5
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Skin sensitization to cinnamic alcohol: the role of skin metabolism.
pubmed:affiliation
Unilever Environmental Safety Laboratory, Bedford, England.
pubmed:publicationType
Journal Article