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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
|
| pubmed:dateCreated |
1992-11-25
|
| pubmed:databankReference | |
| pubmed:abstractText |
The predicted amino acid sequence of the product of the acetate-inducible acu-8 gene of Neurospora crassa, previously of unknown function, has close homology to the recently published sequence of Saccharomyces cerevisiae acetyl-CoA hydrolase. An acu-8 mutant strain, previously characterized as acetate non-utilizing, shows strong growth-inhibition by acetate, but will use it as carbon source at low concentrations. The mutant was shown to be deficient in acetyl-CoA hydrolase and to accumulate acetyl-CoA when supplied with acetate. As in Saccharomyces, the Neurospora enzyme is acetate-inducible.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0022-1287
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
138
|
| pubmed:geneSymbol |
acu-8
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1797-800
|
| pubmed:dateRevised |
2005-1-21
|
| pubmed:meshHeading | |
| pubmed:year |
1992
|
| pubmed:articleTitle |
An acetate-sensitive mutant of Neurospora crassa deficient in acetyl-CoA hydrolase.
|
| pubmed:affiliation |
Protein Engineering Department, AFRC Institute of Food Research, Reading, UK.
|
| pubmed:publicationType |
Journal Article
|