Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1992-9-16
pubmed:databankReference
pubmed:abstractText
A previously unknown major histocompatibility complex class II molecule consisting of the beta chain encoded by the H-2Ob gene and an unknown alpha chain was recently described. We now report that the alpha chain occurs in two allelic forms distinguished by charge difference. Using inbred recombinant mouse strains we were able to map the H-2Oa gene to a location between the A.TL and B10.MBR recombination points. Cosmids covering this region were used to isolate the gene. Sequence analysis revealed that the H-2Oa gene is the murine equivalent of the human HLA-DNA gene. These results indicate that the human HLA-DNA gene, the existence of which has long been known, is indeed coding for DO alpha, the alpha chain pairing with DO beta.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-1538753, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-1675431, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-1681432, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-1758495, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-1922366, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-2270487, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-271968, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-2891610, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-2897949, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-2998758, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-3000765, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-3036829, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-3754180, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-3780666, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-3860873, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-3865893, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-6219389, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-6309407, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-6403249, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-6546423, http://linkedlifedata.com/resource/pubmed/commentcorrection/1354242-6585297
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0022-1007
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
176
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
477-83
pubmed:dateRevised
2010-9-7
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
The alpha chain gene of H-2O has an unexpected location in the major histocompatibility complex.
pubmed:affiliation
Department of Immunology, Scripps Research Institute, La Jolla, California 92037.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't