Linked Life Data

1354107

Source:http://linkedlifedata.com/resource/pubmed/id/1354107

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1992-9-14
pubmed:abstractText
1. The newly described atrial natriuretic peptide hormonal system appears to play an important role in the endocrine control of sodium and water metabolism in human and vertebrate animals, but neither atrial natriuretic factor (ANF, C-terminal amino acids (a.a.) 99-126 a.a. prohormone) nor the rest of the ANF prohormone have ever been demonstrated in the heart of an invertebrate. 2. The present investigation was designed to determine whether the earthworm, Lumbricus terrestis, the first animal in the phylogenic tree with any form of heart, has either ANF and/or the 98 a.a. N-terminus of the ANF prohormone. 3. Both an ANF-like peptide (189 +/- 32 ng/g of tissue) and the N-terminus of the ANF prohormone-like peptide (1985 +/- 27 ng/g of tissue) were present in the earthworm heart at concentrations significantly higher (P less than 0.001) than in rat (Rattus norvegicus) heart ventricles. 4. This newly-described hormonal system, thus, appears to be present in a much larger proportion of the animal kingdom than previously thought, including invertebrates as well as vertebrates.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0742-8413
pubmed:author
pubmed:issnType
Print
pubmed:volume
101
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
325-9
pubmed:dateRevised
2007-7-23
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
The most primitive heart in the animal kingdom contains the atrial natriuretic peptide hormonal system.
pubmed:affiliation
Department of Medicine, University of South Florida Health Sciences Center, Tampa.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, Non-P.H.S.