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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1992-9-9
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pubmed:abstractText |
Sulphasalazine is among the many drugs in the secondary line of antirheumatic efficacy that have both immunosuppressive and auto-inflammatory properties. Twenty-six patients with definite rheumatoid arthritis (RA) were treated for two years with sulphasalazine in a minimum dose of 1 g per day. Four patients presented untoward effects such as: marked physical asthenia, erythema and changes of the dysproteinemia tests which all disappeared when the drug was withdrawn. The first favourable results in the joint inflammation appeared after 4 weeks. Significant clinical and biologic changes were observed at the end of the study thus suggesting the therapeutic value of sulphasalazine in RA.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1220-4749
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
127-32
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1353901-Adolescent,
pubmed-meshheading:1353901-Adult,
pubmed-meshheading:1353901-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:1353901-Arthritis, Rheumatoid,
pubmed-meshheading:1353901-Cortisone,
pubmed-meshheading:1353901-Drug Evaluation,
pubmed-meshheading:1353901-Drug Resistance,
pubmed-meshheading:1353901-Drug Therapy, Combination,
pubmed-meshheading:1353901-Female,
pubmed-meshheading:1353901-Follow-Up Studies,
pubmed-meshheading:1353901-Humans,
pubmed-meshheading:1353901-Remission Induction,
pubmed-meshheading:1353901-Sulfasalazine
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pubmed:articleTitle |
Sulphasalazine therapy in rheumatoid arthritis. A two-year study and follow-up of clinical results.
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pubmed:affiliation |
N. Gh. Lupu Institute of Internal Medicine, Bucharest, Romania.
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pubmed:publicationType |
Journal Article
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