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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
15
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pubmed:dateCreated |
1992-9-4
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pubmed:databankReference |
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pubmed:abstractText |
The A alpha mating locus is one of four multiallelic loci that govern sexual development in the basidiomycete fungus Schizophyllum commune. We have determined the nucleotide sequence encoding three A alpha mating types, A alpha 1, A alpha 3, and A alpha 4. We have found that the locus for A alpha 3 and A alpha 4 consists of two genes: Y and Z. The locus for A alpha 1 encodes only one gene, Y. The Z polypeptides encoded by different alleles exhibit 42% identity. The Y polypeptides exhibit 49-54% identity. The finding that the deduced Z and Y polypeptides have homeodomain motifs suggests that these polypeptides may be DNA-binding regulatory proteins that control the expression of developmental genes. The deduced Z polypeptide also has acidic regions that might be functionally analogous to the acidic regions in yeast GAL4 and GCN4 that activate transcription. The Y polypeptide has a serine-rich region and a basic region that shows some identity to the lysine-rich region of H1 histones.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-1353887,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-1367417,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-1582410,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-16453552,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-16590286,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-1678725,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-1739973,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-1967554,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-1977088,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-2261476,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-2401401,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-2513489,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-2550767,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-2568852,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-271968,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-2914602,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-2915990,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-3028647,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-3127056,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-3162770,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-3313277,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-3530496,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1353886-5230447
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0027-8424
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
7169-73
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pubmed:dateRevised |
2010-9-7
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pubmed:meshHeading |
pubmed-meshheading:1353886-Alleles,
pubmed-meshheading:1353886-Amino Acid Sequence,
pubmed-meshheading:1353886-Crosses, Genetic,
pubmed-meshheading:1353886-DNA, Fungal,
pubmed-meshheading:1353886-DNA-Binding Proteins,
pubmed-meshheading:1353886-Exons,
pubmed-meshheading:1353886-Fungal Proteins,
pubmed-meshheading:1353886-Genes, Fungal,
pubmed-meshheading:1353886-Genes, Homeobox,
pubmed-meshheading:1353886-Histones,
pubmed-meshheading:1353886-Homeodomain Proteins,
pubmed-meshheading:1353886-Introns,
pubmed-meshheading:1353886-Molecular Sequence Data,
pubmed-meshheading:1353886-Protein Biosynthesis,
pubmed-meshheading:1353886-Restriction Mapping,
pubmed-meshheading:1353886-Schizophyllum,
pubmed-meshheading:1353886-Sequence Homology, Nucleic Acid,
pubmed-meshheading:1353886-Software,
pubmed-meshheading:1353886-Transcription, Genetic,
pubmed-meshheading:1353886-Transcription Factors
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pubmed:year |
1992
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pubmed:articleTitle |
The A alpha mating locus of Schizophyllum commune encodes two dissimilar multiallelic homeodomain proteins.
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pubmed:affiliation |
Department of Microbiology and Molecular Genetics, University of Vermont, Burlington 05405.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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