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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
1992-9-2
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pubmed:abstractText |
From 1980 to 1989, 279 patients underwent pancreaticoduodenectomy at a single institution with a postoperative mortality of 4%. The aim of this study was to determine incidence, origin, and present management strategy of early complications following this operation. Significant morbidity occurred in 46% of the patients, including delayed gastric emptying (23%), pancreaticojejunal anastomotic leak (17%), intra-abdominal sepsis (10%), biliary-enteric anastomotic leak (9%), gastrointestinal tract bleeding (5%), and intra-abdominal hemorrhage (3%). Complications were associated with advanced age, prolonged operations, and increased operative blood loss. Most complications were managed nonoperatively. Mortality was increased when a reoperation was required, a biliary-enteric leak occurred, or an intra-abdominal abscess developed. Pancreaticoduodenectomy continues to carry a high postoperative morbidity; however, operative mortality is low, and management of complications has been made simpler with more sophisticated, nonoperative therapeutic options.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0004-0010
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
127
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
945-9; discussion 949-50
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1353671-Abscess,
pubmed-meshheading:1353671-Adult,
pubmed-meshheading:1353671-Aged,
pubmed-meshheading:1353671-Aged, 80 and over,
pubmed-meshheading:1353671-Anastomosis, Surgical,
pubmed-meshheading:1353671-Female,
pubmed-meshheading:1353671-Gastric Emptying,
pubmed-meshheading:1353671-Gastrointestinal Hemorrhage,
pubmed-meshheading:1353671-Humans,
pubmed-meshheading:1353671-Length of Stay,
pubmed-meshheading:1353671-Male,
pubmed-meshheading:1353671-Middle Aged,
pubmed-meshheading:1353671-Pancreaticoduodenectomy,
pubmed-meshheading:1353671-Reoperation,
pubmed-meshheading:1353671-Retrospective Studies,
pubmed-meshheading:1353671-Survival Rate
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pubmed:year |
1992
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pubmed:articleTitle |
Complications following pancreaticoduodenectomy. Current management.
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pubmed:affiliation |
Department of Surgery, Mayo Clinic, Rochester, MN 55905.
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pubmed:publicationType |
Journal Article
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