Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
1992-7-28
|
pubmed:abstractText |
Seven cases of capillary hemangioblastoma from the cerebellum and spinal cord were studied by immunohistochemical methods to determine the origin of the stromal cells. A subpopulation of factor XIIIa-positive tumor cells was a constant feature in hemangioblastomas. These stellate or spindle-shaped cells transformed into typical vacuolated stromal cells. Factor VIII-related antigen was limited to the vascular endothelium. Glial fibrillary acidic protein was present only in entrapped astrocytes. Staining for alpha-1-antitrypsin (alpha 1AT) and alpha-1-antichymotrypsin (alpha 1 ACT) was occasionally observed in stromal cells. It was concluded that the factor XIIIa-positive stromal cells in capillary hemangioblastoma indicate fibrohistiocytic differentiation, which is part of the differentiation spectrum of hemangiopericytomas.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0046-8177
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
23
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
805-10
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:1351864-Adult,
pubmed-meshheading:1351864-Biological Markers,
pubmed-meshheading:1351864-Cerebellar Neoplasms,
pubmed-meshheading:1351864-Female,
pubmed-meshheading:1351864-Hemangiosarcoma,
pubmed-meshheading:1351864-Humans,
pubmed-meshheading:1351864-Immunoenzyme Techniques,
pubmed-meshheading:1351864-Male,
pubmed-meshheading:1351864-Middle Aged,
pubmed-meshheading:1351864-Spinal Cord Neoplasms,
pubmed-meshheading:1351864-Transglutaminases
|
pubmed:year |
1992
|
pubmed:articleTitle |
Fibrohistiocytic differentiation in capillary hemangioblastoma.
|
pubmed:affiliation |
Department of Pathology, University Medical School of Debrecen, Hungary.
|
pubmed:publicationType |
Journal Article
|