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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
1992-6-25
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pubmed:databankReference |
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pubmed:abstractText |
The nucleotide sequence of a 7.2-kb segment containing the mouse IL-10 (mIL-10) gene was determined. Comparison to the mIL-10 cDNA sequence (Moore, K. W., et al. 1990. Science 248:1230; 250:494) revealed the presence of five exons that span approximately 5.1 kb of genomic DNA. The noncoding regions of the mIL-10 gene contain sequences that have been associated with transcriptional regulation of several cytokine genes. The mIL-10 gene was mapped to mouse chromosome 1 and the human IL-10 gene was also mapped to human chromosome 1.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0022-1767
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
148
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3618-23
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:1350294-Amino Acid Sequence,
pubmed-meshheading:1350294-Animals,
pubmed-meshheading:1350294-Base Sequence,
pubmed-meshheading:1350294-Chromosome Mapping,
pubmed-meshheading:1350294-Chromosomes, Human, Pair 1,
pubmed-meshheading:1350294-Gene Expression Regulation,
pubmed-meshheading:1350294-Genes,
pubmed-meshheading:1350294-Humans,
pubmed-meshheading:1350294-Interleukin-10,
pubmed-meshheading:1350294-Mice,
pubmed-meshheading:1350294-Molecular Sequence Data,
pubmed-meshheading:1350294-Oligodeoxyribonucleotides,
pubmed-meshheading:1350294-Open Reading Frames,
pubmed-meshheading:1350294-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:1350294-Regulatory Sequences, Nucleic Acid,
pubmed-meshheading:1350294-Restriction Mapping
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pubmed:year |
1992
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pubmed:articleTitle |
Structure of the mouse IL-10 gene and chromosomal localization of the mouse and human genes.
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pubmed:affiliation |
Department of Immunology, DNAX Research Institute of Molecular and Cellular Biology, Palo Alto, CA 94304.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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