rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
2
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pubmed:dateCreated |
1992-6-12
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pubmed:abstractText |
The amplification grade of oncogene c-erbB-2 was examined by the polymerase-chain-reaction-method in DNA's of 56 primary mammary carcinomas. 26 (46.4%) of these showed the amplified oncogene c-erbB-2. In the strongly amplified cases, the expression of the c-erbB-2 oncoprotein was verifiable immunohistochemically. Between the progesterone receptor status (PR) and the amplified c-erbB-2 oncogene there was a statistically proven dependency. No correlation was observed between the amplified c-erbB-2 oncogene and the epidermal growth-factor receptor (EGFR).
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pubmed:language |
ger
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Epidermal Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, erbB-2,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Estrogen,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Progesterone,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological
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pubmed:status |
MEDLINE
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pubmed:issn |
0044-4197
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
114
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
82-5
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:1350129-Breast,
pubmed-meshheading:1350129-Breast Neoplasms,
pubmed-meshheading:1350129-Carcinoma, Intraductal, Noninfiltrating,
pubmed-meshheading:1350129-Female,
pubmed-meshheading:1350129-Gene Amplification,
pubmed-meshheading:1350129-Humans,
pubmed-meshheading:1350129-Immunoenzyme Techniques,
pubmed-meshheading:1350129-Lymph Nodes,
pubmed-meshheading:1350129-Lymphatic Metastasis,
pubmed-meshheading:1350129-Neoplasm Staging,
pubmed-meshheading:1350129-Proto-Oncogene Proteins,
pubmed-meshheading:1350129-Receptor, Epidermal Growth Factor,
pubmed-meshheading:1350129-Receptor, erbB-2,
pubmed-meshheading:1350129-Receptors, Estrogen,
pubmed-meshheading:1350129-Receptors, Progesterone,
pubmed-meshheading:1350129-Tumor Markers, Biological
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pubmed:year |
1992
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pubmed:articleTitle |
[C-erbB-2 oncogene amplification in breast cancer in correlation to steroid and epidermal growth factor receptor].
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pubmed:affiliation |
I. Universitäts-Frauenklinik Wien.
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pubmed:publicationType |
Journal Article,
English Abstract
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