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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1992-4-23
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pubmed:abstractText |
In cmu- B220+ Thy-1- murine immature B cells transformed with a temperature-sensitive mutant of Abelson murine leukemia virus, a low level of Thy-1 antigen was transitorily expressed after the shift of the culture temperature from the permissive (35 degrees C) to the non-permissive (39 degrees C) temperature. On the other hand, B220 antigen was persistently expressed regardless of whether the cells were cultured at the permissive or non-permissive temperature. No other T-lineage-specific antigens, CD3, CD4, and CD8 were induced during the culture at the non-permissive temperature. Expression of Thy-1 antigen was confirmed by the detection of a low level of Thy-1-specific mRNA. These results clearly showed that immature B cells could express Thy-1 antigen during proliferation and/or differentiation. The results imply a role for Thy-1 antigen in B cell proliferation and/or differentiation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0882-0139
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
85-92
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:1347756-Animals,
pubmed-meshheading:1347756-Antigens, Surface,
pubmed-meshheading:1347756-Antigens, Thy-1,
pubmed-meshheading:1347756-B-Lymphocytes,
pubmed-meshheading:1347756-Cell Differentiation,
pubmed-meshheading:1347756-Cell Division,
pubmed-meshheading:1347756-Cell Line,
pubmed-meshheading:1347756-Cell Line, Transformed,
pubmed-meshheading:1347756-Flow Cytometry,
pubmed-meshheading:1347756-Membrane Glycoproteins,
pubmed-meshheading:1347756-Mice,
pubmed-meshheading:1347756-Mice, Inbred BALB C,
pubmed-meshheading:1347756-RNA, Messenger
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pubmed:year |
1992
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pubmed:articleTitle |
Transitory expression of Thy-1 antigen in immature B cell lines.
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pubmed:affiliation |
Department of Medicine III, Osaka University Medical School, Japan.
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pubmed:publicationType |
Journal Article
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