Linked Life Data

1347248

Source:http://linkedlifedata.com/resource/pubmed/id/1347248

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1992-4-9
pubmed:abstractText
In order to determine if somatostatin (SOM)-immunoreactive (I) cell bodies and processes in lamina (L) II of the rat spinal cord receive dorsal root input, the latter were anterogradely labeled by wheat germ agglutinin-conjugated horseradish peroxidase (WGA-HRP). SOM-I structures were demonstrated by immunohistochemistry. Cell bodies labeled transscellularly or transsynaptically by WGA-HRP and immunohistochemically for SOM were present in L II. In addition, a L I cell was double labeled. These results suggest that some dorsal root axons innervate SOM-I neurons in L I-II of the spinal cord. In addition to confirming immunohistochemical observations in published reports, we have revealed SOM-I central terminals in the type II glomerulus. Further, a SOM-I CI-terminal, presumed to be of primary afferent origin, contacted a SOM-I dendrite in L II. Since SOM has been implicated in nociceptive function in the dorsal horn, it is possible that some of the SOM-I structures identified are involved in nociceptive processing.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0361-9230
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
17-26
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Evidence for dorsal root projection to somatostatin-immunoreactive structures in laminae I-II of the spinal dorsal horn.
pubmed:affiliation
Department of Anatomy, Tongji Medical University, Wuhan, China.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't