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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1992-3-12
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pubmed:abstractText |
Restriction endonuclease variation in the 12 kb region surrounding the Adh locus was measured in seven Australian and six Chinese populations of Drosophila melanogaster. There is a higher level of nucleotide-substitution variation in the Australian populations than in the Chinese, which is possibly a reflection of their origins. None of the restriction site polymorphisms, nor any of the insertions, showed a significant association with latitude. A 0.2 kb deletion varied with latitude in the Chinese populations. In accordance with previous studies, a majority of the insertions were located in a region 1.5-3.5 kb 3' from the Adh coding region, and a majority of the deletions were at a site 3 kb 5' to the Adh coding region. Two of the insertions shared homologies with known mobile elements. Overall, the data suggest that restriction endonuclease variation in the Adh region is not related to the cline in Adhs frequencies.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0018-067X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
68 ( Pt 1)
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pubmed:geneSymbol |
Adh
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-14
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1346530-Alcohol Dehydrogenase,
pubmed-meshheading:1346530-Animals,
pubmed-meshheading:1346530-Australia,
pubmed-meshheading:1346530-China,
pubmed-meshheading:1346530-DNA,
pubmed-meshheading:1346530-DNA Restriction Enzymes,
pubmed-meshheading:1346530-Drosophila melanogaster,
pubmed-meshheading:1346530-Female,
pubmed-meshheading:1346530-Haplotypes,
pubmed-meshheading:1346530-Heterozygote,
pubmed-meshheading:1346530-Male,
pubmed-meshheading:1346530-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:1346530-Restriction Mapping
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pubmed:year |
1992
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pubmed:articleTitle |
The alcohol dehydrogenase polymorphism in natural populations of Drosophila melanogaster: restriction map variation in the region of the Adh locus in populations from two hemispheres.
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pubmed:affiliation |
Molecular and Population Genetics Group, Research School of Biological Sciences, Australian National University, Canberra.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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