Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1994-10-14
pubmed:abstractText
Although growth-associated protein-43 (GAP-43) was initially considered to be neuron-specific, it has more recently been found in astrocytes, oligodendrocytes, Schwann cells, glial cell equivalents in embryonic Drosophila and other non-neuronal cells. Here I summarize evidence for the presence of GAP-43 in macroglial cells (i.e., astrocytes and oligodendrocytes) cultured from neonatal rat cortex and describe its developmental expression in a lineage-specific and cell-type-specific manner. These and other data suggest that GAP-43 is a multifunctional protein involved in the synthesis of membranes associated with the growth of various types of cellular processes, including those of macroglial cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1064-0517
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
39-43
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
GAP-43 expression in macroglial cells: potential functional significance.
pubmed:affiliation
National Institute of Mental Health, Rockville, MD 20857.
pubmed:publicationType
Journal Article, Review