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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3-4
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pubmed:dateCreated |
1994-8-9
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pubmed:abstractText |
The effect of truncal vagotomy and pyloroplasty on rat gastric mucosal H,K-ATPase and HCO3-ATPase activities was studied 15 and 30 days past the operation. A significant decrease in gastric body mucosal H,K-ATPase activity occurred 15 days after vagotomy, compared with pyloroplasty (p < 0.05) and non-operated control rats (p < 0.01). A recovery in the enzyme activity on the 30th postoperative day occurred. Gastric body and antral mucosal HCO3-ATPase activity was significantly (p < 0.01) decreased 15 and 30 days after vagotomy and pyloroplasty, compared with pyloroplasty controls. The observed changes in gastric mucosal H,K-ATPase and HCO3-ATPase activities after vagotomy reflect the decrease in gastric acid secretion, as well as the possible changes in mucosal bicarbonate secretion and acid-base status. A gradual recovery in mucosal H,K-ATPase activity after vagotomy may occur.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adenosine Triphosphatases,
http://linkedlifedata.com/resource/pubmed/chemical/Anion Transport Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Bicarbonates,
http://linkedlifedata.com/resource/pubmed/chemical/H( )-K( )-Exchanging ATPase,
http://linkedlifedata.com/resource/pubmed/chemical/anion-sensitive ATPases
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pubmed:status |
MEDLINE
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pubmed:issn |
0231-4614
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
257-64
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1345384-Adenosine Triphosphatases,
pubmed-meshheading:1345384-Animals,
pubmed-meshheading:1345384-Anion Transport Proteins,
pubmed-meshheading:1345384-Bicarbonates,
pubmed-meshheading:1345384-Gastric Mucosa,
pubmed-meshheading:1345384-H(+)-K(+)-Exchanging ATPase,
pubmed-meshheading:1345384-Male,
pubmed-meshheading:1345384-Pylorus,
pubmed-meshheading:1345384-Rats,
pubmed-meshheading:1345384-Rats, Wistar,
pubmed-meshheading:1345384-Vagotomy, Truncal
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pubmed:articleTitle |
Effect of truncal vagotomy and pyloroplasty on rat gastric mucosal H,K-ATPase and HCO3-ATPase activities.
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pubmed:affiliation |
Department of Surgery, Pelgulinna Hospital Tallinn, Estonia.
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pubmed:publicationType |
Journal Article
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