Linked Life Data

13416309

Source:http://linkedlifedata.com/resource/pubmed/id/13416309

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1957-12-1
pubmed:abstractText
1. The distribution of DPN and DPNH pyrophosphatases and DPNase in centrifugally prepared fractions of organs of several species of animals is reported. 2. A DPNH pyrophosphatase was found in the soluble fraction of pigeon and of rabbit liver. This enzyme did not split DPN but accounted for over 50 per cent of the DPNH pyrophosphatase activity of the whole homogenates. 3. All the organs tested, including the pigeon liver and rabbit liver, contained a microsomal pyrophosphatase that attacked both DPNH and DPN. This microsomal enzyme split DPNH faster than DPN in all cases. 4. DPN pyrophosphatase and DPNase activity were generally concentrated in the microsomal fraction of liver, of kidney, and of brain. 5. The DPNase of hamster liver was virtually inactive at pH 7.5 but was optimally active at pH 5.5. Considerable difference was found with respect to pH on the activity of DPNase from organs of different animals. 6. The inhibition of mitochondrial and microsomal DPNH oxidation by nicotinamide was noted during the course of these experiments. 7. The significance of some of the distribution patterns is discussed.
pubmed:commentsCorrections
pubmed:keyword
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
OM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0095-9901
pubmed:author
pubmed:issnType
Print
pubmed:day
25
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
31-43
pubmed:dateRevised
2010-6-22
pubmed:meshHeading
pubmed:year
1957
pubmed:articleTitle
Distribution of enzymes cleaving pyridine nucleotides in animal tissues.
pubmed:publicationType
Journal Article