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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1976-11-1
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pubmed:abstractText |
The biosynthesis of ribosomal ribonucleic acid (rRNA) In wild-type Neurospora crassa growing at 25 degrees C was investigated by continuous-labeling and pulsechase experiments using [5-3H]uridine. The results of these experiments suggest the following precursor-product relationships: the first RNA molecule to be synthesized in significant quantities is the 2.4 X 10(6)-dalton (2.4-Mdal) ribosomal precursor RNA. This RNA is cleaved to produce two species of RNA with weights of 0.7 and 1.4-Mdal. The former is the mature 17S rRNA of the 37S ribosomal subunit. The 1.4-Mdal RNA is subsequently cleaved to produce the mature 1.27-Mdal (25S) and 61,000-dalton (5.8S) rRNA's of the 60S ribosomal subunit. In the maturation process, approximately 15 to 20% of the 2.4-Mdal ribosomal precursor rRNA molecule is lost. As in other eukaryotes that have been examined, 5S rRNA is not derived from this precursor molecule.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-1122947,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-1191704,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-1192240,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-1192241,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-1237431,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-126993,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-130375,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-172644,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-4176425,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-4268438,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-4274511,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-4281772,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-4538405,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-4557192,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-4568815,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-4893532,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-4896715,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-4920820,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-4943365,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-5145747,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-5323136,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-5337479,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-5339793,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-5339944,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-5367033,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-5498077,
http://linkedlifedata.com/resource/pubmed/commentcorrection/134025-5540996
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0021-9193
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
127
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
785-93
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
1976
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pubmed:articleTitle |
Neurospora crassa cytoplasmic ribosomes; ribosomal ribonucleic acid synthesis in the wild type.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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