Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1993-11-2
pubmed:abstractText
The concentrations of oxytocin receptors were measured in intercaruncular and caruncular endometrium, fetal cotyledons, chorioallantois and amnion during pregnancy and parturition in cows. Tissues were obtained on days 20 (endometrium only), 50, 100, 150, 200, 225, 250, 275, at term (days 280-284), during labour and within 24 h after calving. Receptor concentrations in intercaruncular endometrium were low on day 20 of pregnancy, 39 +/- 11 fmol mg-1 protein. By day 50, receptor concentrations had increased more than tenfold to 572 +/- 52 fmol and rose steadily until day 250 and then levelled off at about 4500 fmol mg-1. Shortly before parturition, on day 282 +/- 1, a further rise to 7300 +/- 1418 fmol mg-1 was observed, these concentrations were maintained throughout labour. By contrast, caruncular endometrial receptor concentrations remained low until term, mean 145 +/- 15 fmol mg-1, and then rose to 720 +/- 163 fmol mg-1 during labour (cervix 17 cm--fully dilated). Fetal cotyledons and membranes had very low oxytocin receptor concentrations during most of pregnancy, on average only 20 fmol mg-1 protein. At term and during labour, receptor concentrations were significantly increased in both tissues. Mean concentrations during labour were 163 +/- 36 fmol mg-1 for cotyledons, 270 +/- 61 fmol mg-1 for chorioallantois and 311 +/- 121 fmol mg-1 for amnion.(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0022-4251
pubmed:author
pubmed:issnType
Print
pubmed:volume
96
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
775-83
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:1339857-Allantois, pubmed-meshheading:1339857-Amnion, pubmed-meshheading:1339857-Analysis of Variance, pubmed-meshheading:1339857-Animals, pubmed-meshheading:1339857-Binding, Competitive, pubmed-meshheading:1339857-Cattle, pubmed-meshheading:1339857-Chorion, pubmed-meshheading:1339857-Endometrium, pubmed-meshheading:1339857-Estradiol, pubmed-meshheading:1339857-Estrone, pubmed-meshheading:1339857-Extraembryonic Membranes, pubmed-meshheading:1339857-Female, pubmed-meshheading:1339857-Labor, Obstetric, pubmed-meshheading:1339857-Oxytocin, pubmed-meshheading:1339857-Placenta, pubmed-meshheading:1339857-Pregnancy, pubmed-meshheading:1339857-Pregnancy, Animal, pubmed-meshheading:1339857-Progesterone, pubmed-meshheading:1339857-Receptors, Oxytocin, pubmed-meshheading:1339857-Regression Analysis
pubmed:year
1992
pubmed:articleTitle
Concentration of oxytocin receptors in the placenta and fetal membranes of cows during pregnancy and labour.
pubmed:affiliation
Department of Obstetrics and Gynecology, Cornell University Medical College, New York, NY 10021.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't