Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-9-16
pubmed:abstractText
At 28 months of age (old rats), male Fisher 344 rats which had been fed 40% of the ad libitum food intake since they were 6 months old, had a similar beta-adrenergic receptor density (Bmax) in their pineal gland as young, 3-month-old rats. In contrast, old rats which had been fed ad libitum for the same period had approximately 50% of the Bmax value compared to that of young rats. The beta-receptor density of cerebral cortical tissue and the beta-receptor affinity (Kd) of both the cortex and the pineal gland did not decline with age and was not affected by food restriction. The reduction in pineal beta-receptor density with age may be casually related to the concurrent age-associated decline in pineal production of melatonin.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1016-0922
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
34-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
Age-associated reduction in pineal beta-adrenergic receptor density is prevented by life-long food restriction in rats.
pubmed:affiliation
Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio 78284-7762.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't