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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
1993-5-27
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pubmed:abstractText |
A 23-year-old man with persisting high fever developed hepatosplenomegaly, lymphadenopathy and massive pericardial effusion. Immunological examination revealed a marked elevation of anti-Epstein-Barr virus antibodies (anti-viral capsid antigens IgG-antibody 1:10,240, anti-early antigens-DR IgG-antibody 1:5,120), decreased activities of Epstein-Barr virus specific cytotoxic T lymphocytes, natural killer cells and lymphokine activated killer cells. A liver biopsy showed moderate sinusoidal lymphocytosis with punched-out lesions. These findings suggested severe chronic active Epstein-Barr virus infection syndrome. The patient was treated with recombinant human interleukin-2, but it was discontinued because of an adverse reaction. Twelve months later, he died of suspected pulmonary infection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0918-2918
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1381-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1338620-Adult,
pubmed-meshheading:1338620-Antibodies, Viral,
pubmed-meshheading:1338620-Chronic Disease,
pubmed-meshheading:1338620-Hepatomegaly,
pubmed-meshheading:1338620-Herpesviridae Infections,
pubmed-meshheading:1338620-Herpesvirus 4, Human,
pubmed-meshheading:1338620-Humans,
pubmed-meshheading:1338620-Lymphadenitis,
pubmed-meshheading:1338620-Male,
pubmed-meshheading:1338620-Pericardial Effusion,
pubmed-meshheading:1338620-Splenomegaly,
pubmed-meshheading:1338620-Syndrome
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pubmed:year |
1992
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pubmed:articleTitle |
An adult case of severe chronic active Epstein-Barr virus infection syndrome.
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pubmed:affiliation |
Second Department of Internal Medicine, School of Medicine, Nagasaki University, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
|