Linked Life Data

1337270

Source:http://linkedlifedata.com/resource/pubmed/id/1337270

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1993-3-8
pubmed:abstractText
The effect of the weaning diet on the subsequent colonic metabolism of bran and pectin in the adult rat has been investigated. Feeding a fibre-reduced diet on its own or supplemented with bran (WB) and pectin (P) from weaning (fibre-reduced (weaning)) was compared with introducing the same diet to age-matched rats reared on a standard laboratory diet from weaning (fibre-reduced (6 weeks)). The effects of the diets on colonic metabolism were measured by wet and dry caecal contents and stool weights, caecal sac weight, and caecal and faecal short-chain fatty acids (SCFA). Final body-weights were greater for fibre-reduced (6 weeks) and fibre-reduced (6 weeks) + P groups, but not fibre-reduced (6 weeks) + WB, than those of the fibre-reduced (weaning) rats. Rats fed on fibre-reduced (6 weeks) diet had a higher total caecal SCFA content than fibre-reduced (weaning) control rats. Fibre-reduced (weaning) + P-fed rats had a threefold higher caecal concentration of both propionate and butyrate than the matched fibre-reduced (6 weeks) + P group. Fibre-reduced (weaning) + WB animals had a significantly higher butyrate caecal concentration compared with their matched fibre-reduced (6 weeks) + WB group. Fibre-reduced (weaning) + P-fed rats had a lower faecal output than the fibre-reduced (6 weeks) + P rats. There was no difference in faecal output in rats fed on either fibre-reduced (6 weeks) + WB or fibre-reduced (weaning) + WB. The faecal concentration of SCFA was in general higher in the rats fed on fibre-reduced (weaning) alone, + P, or + WB than in those fed on fibre-reduced (6 weeks) alone, + P or + WB. Faecal output of total and individual SCFA was increased on the fibre-reduced (weaned) + WB diet compared with fibre-reduced (6 weeks) + WB-fed animals. The diet at weaning may be important in determining the pathways of caecal bacterial metabolism in the adult rat. In studying the effect of a dietary fibre on caecal metabolism and faecal output, when the diet is changed appears to be important.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0007-1145
pubmed:author
pubmed:issnType
Print
pubmed:volume
68
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
741-51
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
The effect of weaning diet on the subsequent colonic metabolism of dietary fibre in the adult rat.
pubmed:affiliation
Department of Medicine, Western General Hospital, Edinburgh.
pubmed:publicationType
Journal Article, Comparative Study