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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
1993-2-19
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pubmed:abstractText |
The spontaneous calcanean bone loss occurring in healthy early post-menopausal women and the effect of two hormone replacement therapies (HRT's) were investigated in a longitudinal study. There was no difference between the right and left calcanean BMC or BMD (p > 0.15). The spontaneous bone loss was similar at all the skeletal sites measured, with a mean spontaneous loss in calcanean BMD of 1.6% over one year. Both HRT's significantly (p < 0.01) prevented the bone loss from all skeletal sites irrespective of the weight-bearing or content of trabecular bone, and (for the weight-bearing bones) there was even a gain in calcanean BMC and BMD and spinal BMD (p < 0.01). Bone mineral of the calcaneus and the spine correlated equally to body weight (r approximately 0.4, p < 0.001), whereas bone mineral in the forearm was not correlated to body weight. The correlations between the changes in bone mineral at the sites measured were all significant (r approximately 0.2-0.4).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0036-5513
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
831-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1336890-Bone Density,
pubmed-meshheading:1336890-Calcaneus,
pubmed-meshheading:1336890-Drug Therapy, Combination,
pubmed-meshheading:1336890-Estradiol,
pubmed-meshheading:1336890-Estrogen Replacement Therapy,
pubmed-meshheading:1336890-Estrogens, Conjugated (USP),
pubmed-meshheading:1336890-Female,
pubmed-meshheading:1336890-Forearm,
pubmed-meshheading:1336890-Humans,
pubmed-meshheading:1336890-Levonorgestrel,
pubmed-meshheading:1336890-Longitudinal Studies,
pubmed-meshheading:1336890-Lumbar Vertebrae,
pubmed-meshheading:1336890-Menopause,
pubmed-meshheading:1336890-Middle Aged
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pubmed:year |
1992
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pubmed:articleTitle |
Changes in calcanean bone mineral occurring spontaneously and during hormone replacement therapy in early post-menopausal women.
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pubmed:affiliation |
Department of Clinical Chemistry, Glostrup Hospital, University of Copenhagen, Denmark.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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