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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1993-2-11
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pubmed:abstractText |
The concentration of the leukotrienes B4 (LTB4) and C4 (LTC4) was measured in the cerebrospinal fluid (CSF) of 38 multiple sclerosis (MS) patients and 51 with other neurological diseases. The LTB4 and LTC4 levels were significantly elevated in MS compared with the controls. The findings suggest that lipoxygenase products might play a pathogenetic role in the early, encephalitogenic phase of MS. The administration of lipoxygenase inhibitors or leukotriene antagonists might well open new perspectives for the treatment of MS.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
|
pubmed:issn |
0001-6314
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
86
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
586-7
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pubmed:dateRevised |
2006-8-16
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pubmed:meshHeading |
pubmed-meshheading:1336293-Adult,
pubmed-meshheading:1336293-Female,
pubmed-meshheading:1336293-Humans,
pubmed-meshheading:1336293-Leukotriene B4,
pubmed-meshheading:1336293-Male,
pubmed-meshheading:1336293-Middle Aged,
pubmed-meshheading:1336293-Multiple Sclerosis,
pubmed-meshheading:1336293-Neurologic Examination,
pubmed-meshheading:1336293-SRS-A
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pubmed:year |
1992
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pubmed:articleTitle |
Leukotrienes in the cerebrospinal fluid of multiple sclerosis patients.
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pubmed:affiliation |
Sindelfingen Municipal Hospital, Germany.
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pubmed:publicationType |
Journal Article
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