|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
803
|
|
pubmed:dateCreated |
1993-2-5
|
|
pubmed:abstractText |
We have studied by the in situ hybridization method the presence of Epstein-Barr virus (EBV) DNA genome in lymph node tissues from 11 patients with persistent generalized lymphadenopathy. Using a biotinylated EBV DNA probe, we demonstrated EBV nucleic acid in scattered germinal centre cells in eight of the 11 cases. Our results suggest that EBV is not a determinant factor in the pathogenesis of this lymphadenopathy, but support its possible implication in B cell malignant transformation in cases of AIDS-associated lymphoma.
|
|
pubmed:commentsCorrections |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0032-5473
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
68
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
739-41
|
|
pubmed:dateRevised |
2010-9-7
|
|
pubmed:meshHeading |
pubmed-meshheading:1336194-AIDS-Related Complex,
pubmed-meshheading:1336194-DNA, Viral,
pubmed-meshheading:1336194-Herpesvirus 4, Human,
pubmed-meshheading:1336194-Humans,
pubmed-meshheading:1336194-In Situ Hybridization,
pubmed-meshheading:1336194-Lymphatic Diseases,
pubmed-meshheading:1336194-Male,
pubmed-meshheading:1336194-Substance Abuse, Intravenous
|
|
pubmed:year |
1992
|
|
pubmed:articleTitle |
In situ demonstration of Epstein-Barr virus in intravenous drug abusers with generalized lymphadenopathy.
|
|
pubmed:affiliation |
Department of Pathology, Hospital Ramon y Cajal, Madrid, Spain.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
