Linked Life Data

1334381

Source:http://linkedlifedata.com/resource/pubmed/id/1334381

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1993-1-8
pubmed:abstractText
In order to further examine a preliminary association between smoking and the subsequent development of Warthin's tumor, a case-control study was undertaken between the years 1980 and 1989. Consecutive patients with Warthin's tumor served as cases, and consecutive patients with pleomorphic adenomas served as controls. A positive history of smoking was defined as a patient with greater than a 10-pack year history. There were 28 cases and 69 controls (ratio: 1:2.5). The number of male to female patients with Warthin's tumor and pleomorphic adenoma was 22 to 6 (3.7:1) and 22 to 47 (1:2.1), respectively. The mean age at presentation with Warthin's tumor or pleomorphic adenoma was 60.7 years and 40.7 years, respectively. In those patients for whom a definite smoking history was known (93 patients), an odds ratio of 8.1 (p < 0.001) was calculated. In order to exclude sex as a possible confounder, the odds ratio in males only was 6.4 (p = 0.007). In order to exclude age as a possible confounder, the odds ratio in all patients over 45 years (48 patients) was 11.2 (p < 0.001). In summary, smokers have eight times the risk of developing a Warthin's tumor than nonsmokers. This case-control study suggests that smoking may be one of the etiologic factors associated with this benign salivary gland tumor.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0002-9610
pubmed:author
pubmed:issnType
Print
pubmed:volume
164
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
646-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Smoking as an etiologic factor in the development of Warthin's tumor of the parotid gland.
pubmed:affiliation
Department of Surgery, University of Toronto, St. Michael's Hospital, Ontario, Canada.
pubmed:publicationType
Journal Article