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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1993-1-6
pubmed:abstractText
Fifty patients (43 male, 7 female, age 31-77 years) with single solid masses in their lungs based on the findings of a chest X-radiograph [40 malignancies: 5 small cell carcinoma (Ca), 17 epidermoid Ca, 12 adeno Ca, 6 undifferentiated large cell Ca] and 10 benign lesions underwent technetium-99m (V) dimercaptosuccinic acid [99m-(V)DMSA] scans to evaluate the usefulness of 99mTc-(V)DMSA in the detection of lung Ca with different cell types and benign lesions. Only 43% (17/40) of the malignancies in the lungs were detected by 99mTc-(V)DMSA, including 29% (5/17) epidermoid Ca, 50% (6/12) adeno Ca and 17% (1/6) undifferentiated large cell Ca of the lungs. However, all 5 cases of small cell Ca and 11 cases combined with bone metastasis were revealed by 99mTc-(V)DMSA. In addition, 3 of the 10 benign lesions (2 organizing pneumonias, 1 benign tumor) presented with an uptake of 99mTc-(V)DMSA. The diagnostic sensitivity, specificity and accuracy were 43%, 70% and 48%, respectively, in differentiating malignant from benign lesions for the single solid mass in the lungs. In conclusion, 99mTc-(V)DMSA is of little or no use in the differentiation of lung Ca from single solid masses in the lungs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0340-6997
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
890-3
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed-meshheading:1333404-Adenocarcinoma, pubmed-meshheading:1333404-Adult, pubmed-meshheading:1333404-Aged, pubmed-meshheading:1333404-Bone Neoplasms, pubmed-meshheading:1333404-Carcinoma, Non-Small-Cell Lung, pubmed-meshheading:1333404-Carcinoma, Small Cell, pubmed-meshheading:1333404-Carcinoma, Squamous Cell, pubmed-meshheading:1333404-Diagnosis, Differential, pubmed-meshheading:1333404-Female, pubmed-meshheading:1333404-Humans, pubmed-meshheading:1333404-Lung Diseases, pubmed-meshheading:1333404-Lung Neoplasms, pubmed-meshheading:1333404-Male, pubmed-meshheading:1333404-Middle Aged, pubmed-meshheading:1333404-Organotechnetium Compounds, pubmed-meshheading:1333404-Sensitivity and Specificity, pubmed-meshheading:1333404-Succimer, pubmed-meshheading:1333404-Technetium Tc 99m Dimercaptosuccinic Acid, pubmed-meshheading:1333404-Technetium Tc 99m Medronate
pubmed:year
1992
pubmed:articleTitle
Using technetium-99m (V) dimercaptosuccinic acid to detect malignancies from single solid masses in the lungs.
pubmed:affiliation
Department of Nuclear Medicine, Taichung Veterans General Hospital, Taiwan, Republic of China.
pubmed:publicationType
Journal Article