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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1992-12-30
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pubmed:abstractText |
The aim of this study was to investigate anti-elastin antibodies of the IgG and IgM types in sera of patients suffering from lung cancer, using the DOT immunobinding assay. We studied 96 pathological and 40 control sera. Anti-elastin antibodies were found to be present in 45% of patients with small cell lung cancer, 19% of subjects with adenocarcinoma and not-identified lung tumor and 15% of patients with squamous cell lung cancer. They circulated in 5% of control persons only. The highest values of their titers were observed in the advanced stages of disease. In 55% of anti-elastin antibody positive small cell lung cancer patients, antibodies were of the IgM type, suggesting the initial step of the autoimmunization to elastin.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0165-2478
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
211-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1332926-Adenocarcinoma,
pubmed-meshheading:1332926-Antibodies, Neoplasm,
pubmed-meshheading:1332926-Carcinoma, Small Cell,
pubmed-meshheading:1332926-Carcinoma, Squamous Cell,
pubmed-meshheading:1332926-Elastin,
pubmed-meshheading:1332926-Female,
pubmed-meshheading:1332926-Humans,
pubmed-meshheading:1332926-Immunoblotting,
pubmed-meshheading:1332926-Immunoglobulin G,
pubmed-meshheading:1332926-Immunoglobulin M,
pubmed-meshheading:1332926-Lung Neoplasms,
pubmed-meshheading:1332926-Male,
pubmed-meshheading:1332926-Middle Aged
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pubmed:year |
1992
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pubmed:articleTitle |
Anti-elastin antibodies in patients with lung cancer.
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pubmed:affiliation |
Department of Biochemistry and Chemistry, Silesian Medical Academy, Katowice, Poland.
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pubmed:publicationType |
Journal Article
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