Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1976-9-2
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pubmed:abstractText |
N-Methyl-N-beta-chloroethyl-hydrazine and its benzaldehydhydrazone are two new cytostatic methylhydrazines. Administered intraperitoneally, they are more effective in inhibiting the ascites tumor growth (Ehrlich's carcinoma in mice and Yoshida sarcoma in rats) than procarbazine in vitro as well as in vivo. The intraperitoneal administration of hydrazone shows a minor effect on the solid tumor. This may be explained by a different pharmacocinetical behaviour. Hydrazone is less toxic than procarbazine.
|
pubmed:language |
ger
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0084-5353
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
86
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
127-33
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pubmed:dateRevised |
2008-2-25
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pubmed:meshHeading |
pubmed-meshheading:132785-Animals,
pubmed-meshheading:132785-Antineoplastic Agents,
pubmed-meshheading:132785-Carcinoma, Ehrlich Tumor,
pubmed-meshheading:132785-Hydrazines,
pubmed-meshheading:132785-Hydrazones,
pubmed-meshheading:132785-Male,
pubmed-meshheading:132785-Mice,
pubmed-meshheading:132785-Procarbazine,
pubmed-meshheading:132785-Rats,
pubmed-meshheading:132785-Sarcoma, Yoshida
|
pubmed:year |
1976
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pubmed:articleTitle |
[On the cytosic action of N-methyl-N-beta-chloraethyl-hydrazine and its benzaldehydhydrazone (author's transl)].
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|