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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1976-8-23
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pubmed:abstractText |
Intact female Sprague-Dawley rats were given daily injections of either 3.125 mg of deoxycorticosterone or 5.0 mg of 16beta-hydroxy-dehydroepiandrosterone, calculated from the activities reported for each to be equivalent mineralocorticoid dosages. The former caused hypertension, cardiorenal enlargement, increased urine output and depressed PRA. Treatment with 16beta-OH-DHEA had no such effect, raising questions regarding its classification as a mineralocorticoid.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0037-9727
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
152
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
218-20
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pubmed:dateRevised |
2007-11-2
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pubmed:meshHeading |
pubmed-meshheading:132667-Animals,
pubmed-meshheading:132667-Blood Pressure,
pubmed-meshheading:132667-Dehydroepiandrosterone,
pubmed-meshheading:132667-Desoxycorticosterone,
pubmed-meshheading:132667-Female,
pubmed-meshheading:132667-Heart,
pubmed-meshheading:132667-Heart Rate,
pubmed-meshheading:132667-Kidney,
pubmed-meshheading:132667-Organ Size,
pubmed-meshheading:132667-Rats,
pubmed-meshheading:132667-Renin,
pubmed-meshheading:132667-Water-Electrolyte Balance
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pubmed:year |
1976
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pubmed:articleTitle |
Effect of deoxycorticosterone acetate and 16beta-hydroxy-dehydroepiandrosterone on blood pressure and plasma renin activity of rats.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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